Richard T. Hart, Ph.D
Edgar C. Hendrickson Designated Professor
Chair, Department of Biomedical Engineering
Phone: (614) 292-9733
Research interests are in finite element analysis of biological tissues and structures, with a primary focus on work that seeks to describe, simulate, and predict the response of bone tissue to mechanical stimuli. Studies are about to begin to work on the role of mechanical loading on the fate of percutaneous bone implants. Investigations use a MicroCT scanner to generate finite element models of cancellous bone. Ocular biomechanics studies, part of the project led by Prof. Jun Liu, include structural analysis of the eye with intraocular pressure variations and the role of corneoscleral material properties. Cellular communication via mechanical signaling studies, part of the project led by Prof. Keith Gooch, include development of finite element models of fibrous gels to study how stresses and forces may be transmitted between fibroblasts that are separated by approximately 10 cell-diameters.
Bone study collaborators include:
Matthew J. Allen, M.B. Ph.D., Associate Professor, College of Veterinary Clinical Sciences
Do-Gyoon Kim, Ph.D., Assistant Professor, College of Dentistry
Hiranmoy Das, Ph.D., Associate Professor of Internal Medicine
Garrett J. Noble, B.S., Graduate Student in Biomedical Engineering
Ocular Biomechanics collaborators include:
Jun Liu, Ph.D., Assistant Professor in Biomedical Engineering
Paul Weber, M.D., Professor in Ophthalmology
Cynthia J. Roberts, Ph.D., Professor of Ophthalmology and Biomedical Engineering
Mechanical communication between cells collaborators include:
Keith J. Gooch, Ph.D., Associate Professor in Biomedical Engineering
Samir N. Ghadiali, Ph.D., Associate Professor in Biomedical Engineering
Xiaoyue Ma, M.S., Graduate Student in Biomedical Engineering
In finite element analysis of biological tissues and structures, including:
Work that seeks to describe, simulate, and predict the response of bone tissue to mechanical stimuli.
Ocular biomechanics, and glaucoma.
Modeling the mechanical communication between cells seeded in collagenous gels.
Mercurio, A., Motta, T., Green, E., Noble, G., Hart, R., Allen, M., “Effects of Circumferential Periosteal Stripping on the Microstructure and Mechanical Properties of Cortical Bone,” Journal of Orthopaedic Research, DOI 10.1002/jor.21537, 2011.
Roberts, M.D., Santner, T.J., and Hart, R.T., “Local Bone Formation Due to Combined Mechanical Loading and Intermittent hPTH-(1-34) Treatment and its Correlation to Mechanical Signal Distributions,” Journal of Biomechanics, 42:2431-2438, 2009.
Girard, M., Suh, J-K F., Hart, R.T., Burgoyne, C.F., Downs, J.C., “Effects of Storage Time on the Mechanical Properties of Rabbit Peripapillary Sclera After Enucleation,” Current Eye Research, 32:465-470, 2007.
Sander, E.A., Downs, J.C., Hart, R.T., Burgoyne, C.F., Nauman, E.A., “A Cellular Solid Model of the Lamina Cribrosa: Mechanical Dependence on Morphology,” Journal of Biomechanical Engineering, 128:879-889, 2006.
Roberts, M.D., and Hart, R.T., “Shape Adaptation of Long Bone Structures Using a Contour Based Approach,” Computer Methods in Biomechanics and Biomedical Engineering, 8:145-156, 2005.
Downs, J.C., J-K Francis Suh, Thomas, K.A., Bellezza, A.J., Hart, R.T., and Burgoyne, C.F., “Viscoelastic Material Properties of the Peripapillary Sclera in Normal and Early Glaucomatous Monkey Eyes,” Investigative Ophthalmology and Visual Science, 46:540-564, 2005.
Burgoyne, C.F., Downs, J.C., Bellezza, A.J., Suh, J-K.F., and Hart, R.T., “The Optic Nerve Head as a Biomechanical Structure: A New Paradigm for Understanding the Role of IOP-related Stress and Strain in the Physiology of Optic Nerve Head Aging and the Pathophysiology of Glaucomatous Damage,” Progress in Retinal and Eye Research, 24:39-73, 2005.
Burgoyne, C.F., Downs, J.C., Bellezza, A.J., and Hart, R.T., “Digital Three-Dimensional Reconstruction of the Normal and Early Glaucomatous Monkey Optic Nerve Head Connective Tissues,” Investigative Ophthalmology and Visual Science, 45:4388-4399, 2004.
Coleman, J.C., Hart, R.T., and Burr, D.B., “Reconstructed Bone End Loads on the Canine Forelimb During Gait,” Journal of Biomechanics, 36:1837-1844, 2003.
Bellezza, A.J., Rintalan, C.J., Downs, J.C., Hart, R.T., and Burgoyne, C.F., “Anterior Scleral Canal Geometry in Pressurized (IOP 10) and Non-Pressurized (IOP 0) Normal Monkey Eyes, British Journal of Ophthalmology,